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Wesley Self Archives

COVID infections in health workers often go undetected: study

Sep. 3, 2020—Many COVID-19 infections among health care workers go undetected, likely because many people infected with SARS-CoV-2, the virus that causes COVID-19, have mild or no symptoms, a study led by Vanderbilt University Medical Center’s Wesley Self, MD, MPH, shows.

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VUMC awarded $34 million to lead nationwide convalescent plasma study

Aug. 21, 2020—Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19.

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Investigational glaucoma drug studied to prevent respiratory distress in COVID-19 patients

Jul. 16, 2020—Vanderbilt University Medical Center is evaluating razuprotafib, a drug being investigated for the treatment of glaucoma, in a new randomized, investigational trial for the prevention and treatment of acute respiratory distress syndrome (ARDS) in adult patients with moderate to severe COVID-19.

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About half of health care workers positive for COVID-19 by serology have no symptoms

Jul. 9, 2020—The IVY Research Network has completed initial studies evaluating the epidemiology of COVID-19 in health care workers and patients.

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Major U.S. trial closes showing no benefit for hydroxychloroquine in COVID-19

Jun. 21, 2020—The Outcomes Related to COVID-19 Treated with Hydroxychloroquine among In-patients with Symptomatic Disease (ORCHID) trial stopped enrolling new patients based on the fourth scheduled interim analysis showing no evidence of benefit or harm. 

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Study launched to test hydroxychloroquine as treatment for COVID-19

Apr. 8, 2020—  by Craig Boerner Faced with a global pandemic of a virus previously unknown to humans, Vanderbilt University Medical Center (VUMC) is leading a clinical trial to understand if hydroxychloroquine, a well-known drug used for malaria and rheumatologic conditions, is safe and effective in treating hospitalized adults with COVID-19. The ORCHID trial (Outcomes Related to...

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Vaccine study seeks to halt flu’s most severe side effects

Oct. 9, 2019—Vanderbilt University Medical Center is leading a multicenter national study to evaluate the effectiveness of the influenza vaccine for preventing the flu’s most serious side effects — admission to an intensive care unit (ICU), organ failure and death.

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Saline use on decline at Vanderbilt following landmark studies

Feb. 27, 2018—Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications.

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Flu vaccine helps reduce hospitalizations due to influenza pneumonia: study

Oct. 6, 2015—More than half of hospitalizations due to influenza pneumonia could be prevented by influenza vaccination, according to a study led by investigators at Vanderbilt University Medical Center, published this week in the Journal of the American Medical Association.

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Study highlights pneumonia hospitalizations among U.S. adults

Jul. 15, 2015—Viruses, not bacteria, are the most commonly detected respiratory pathogens in U.S. adults hospitalized with pneumonia, according to a New England Journal of Medicine study released today and conducted by researchers at Centers for Disease Control and Prevention (CDC) and hospitals in Chicago and Nashville, including Vanderbilt University Medical Center.

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Study finds national decline in one type of serious heart attack

Nov. 20, 2014—The most emergent form of heart attacks is decreasing nationwide, but this declining incidence could affect emergency departments’ quality and timeliness of care.

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Vanderbilt study finds nationwide decline in one type of serious heart attack

Nov. 18, 2014—The most emergent form of heart attacks is decreasing nationwide, but this declining incidence could affect emergency departments’ quality and timeliness of care. This is the key finding of a Vanderbilt University study released today in the American Journal of Cardiology and presented at the national American Heart Association meeting in Chicago this week. Using...

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