Research

March 28, 2024

Study identifies molecule as potential target for treating AML

While immune checkpoint inhibitors that target the PD-1 molecule on T-cells have proven to be effective with many cancers, these immunotherapies have not worked for acute myeloid leukemia (AML), but new research has identified a “cousin” molecule as a potential therapeutic target for AML. 

By Tom Wilemon
March 27, 2024

Higher genetic risk of obesity means working out harder for same results 

Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity. 

By Craig Boerner
From left, John Kuriyan, PhD, Vanderbilt Prize recipient Frances Ashcroft, PhD, Vanderbilt Prize Student Scholar Yasminye Pettway, Kathleen Gould, PhD, and Jennifer Pietenpol, PhD. (photo by Donn Jones)
March 26, 2024

Vanderbilt Prize winner’s lecture focused on the joy of discovery

During her Discovery Lecture on March 21, Professor Dame Frances Ashcroft, recipient of the 2023 Vanderbilt Prize in Biomedical Science, spoke on the joy science has given her.

By Bill Snyder
March 26, 2024

GRADE Study expands results of major NIH-sponsored comparative study of glucose lowering medications in Type 2 diabetes

The study, which included more than 5,000 volunteers with Type 2 diabetes from diverse racial and ethnic groups, compared the treatments insulin glargine, liraglutide, glimepiride and sitagliptin.
(Adobestock)
March 26, 2024

Beethoven’s genes reveal low predisposition for beat synchronization

What the exceptional composer’s DNA tells us about genetics

By Craig Boerner
March 25, 2024

Brain atlas pinpoints vulnerabilities in ALS and dementia

By Paul Govern
March 25, 2024

VUMC team finds potential treatment for kidney fibrosis

By Bill Snyder
March 12, 2024

Genetic Counseling Research Symposium debuts on April 5

The Master of Genetic Counseling (MGC) degree program at Vanderbilt University School of Medicine (VUSM) will hold its first Genetic Counseling Research Symposium April 5 from 8 a.m. to 6 p.m. in room 202, Light Hall.
By Bill Snyder
March 11, 2024

Phase 3 CELLEBRATE trial testing regenerative stem cell-based therapy to improve urinary control for women

The Phase 3 CELLEBRATE trial to test a regenerative stem cell-based therapy in treating patients with stress urinary incontinence is continuing to recruit additional subjects after changing its study protocol to include only patients who have already tried surgery. 
By Craig Boerner
March 7, 2024

Study details metabolism of biomarkers for oxidative stress

Factors other than oxidative stress can modify the levels of biomarkers called isoprostanes that are commonly used in both experimental and clinical research, suggesting that additional standards need to be developed.
By Leigh MacMillan
March 7, 2024

Blood mutations increase risk for acute kidney injury: study

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.
By Bill Snyder
March 4, 2024

Dame Frances Ashcroft to deliver March 21 Vanderbilt Prize Lecture

Professor Dame Frances Ashcroft, recipient of the 2023 Vanderbilt Prize in Biomedical Science, will deliver her Vanderbilt Prize Discovery Lecture at 4 p.m. Thursday, March 21, in 208 Light Hall.
By Bill Snyder
February 27, 2024

Multi-institutional study of Wilms tumor facilitates enrollment, optimizes treatment

Multi-institutional study finds that enrollment and outcomes were similar across racial and ethnic groups for children participating in therapeutic trials for Wilms tumor — the most common pediatric kidney cancer worldwide.
By Leigh MacMillan
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