The discovery could improve safety of allopurinol for millions by expanding genetic screening.

Jacek Hawiger and his colleagues report that a “peptide genomic therapy” given in combination with an antibiotic nearly doubles survival rates from sepsis in an animal model, compared to treatment with antibiotic alone.

The VUMC approach, based on the “Feeling Safe Program” developed by British psychologist Daniel Freeman, targets specific factors that contribute to persecutory delusions, including worry, safety behaviors, avoidance and hallucinations (such as hearing voices).

The new project will map Type 1 diabetes progression using multimodal artificial intelligence alongside a wide range of health data.

With more than 2,400 members, the NAM (formerly the Institute of Medicine) collaborates closely with its peer academies, the National Academy of Sciences and National Academy of Engineering, to provide independent and authoritative advice on matters of science, technology and health nationally and globally.

The researchers anticipate that their findings will inform personalized colorectal polyp surveillance, guide therapeutic prevention strategies, and ultimately reduce the burden of colorectal cancer nationwide.

The grant extension will expand applications in research, clinical trials, registries and national collaborations.