Research

tug-of-rope pair
November 3, 2016

VUMC investigators find pathogens work together to infect host

Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.

By Leigh MacMillan
November 3, 2016

Study details rare heart risk of certain cancer therapies

By VUMC News and Communications
October 27, 2016

Study tracks makeup of VUMC collaborative care teams

At Vanderbilt University Medical Center (VUMC) there are about 486 distinct operational units involved in inpatient care and evaluation.

By Paul Govern
October 27, 2016

Emerging field of cardio-oncology seeks better tools

Improved therapies have led to a spike in the number of people living with cancer, and today there are more than 15.5 million survivors in the United States. However, some of these therapies can cause toxicities to the heart, the vessels and the body’s metabolism.

By VUMC News and Communications
October 26, 2016

Single-cell study of tumor samples

A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer.

By Leigh MacMillan
October 20, 2016

Preparing for a return of pox

To prepare for the potential of a smallpox return, Vanderbilt researchers are isolating and studying naturally occurring antibodies from the blood of previously infected or immunized people.

By Bill Snyder
October 13, 2016

EGF receptor found to regulate macrophage inflammation in gut

Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract.
By Bill Snyder
September 26, 2016

Study shows excess dietary zinc worsens C. diff infection

Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.
By Leigh MacMillan
September 8, 2016

Investigators create ‘Trojan Horse’ to fight Ebola

A multi-center research team including scientists from the Vanderbilt Vaccine Center has come up with a clever “Trojan Horse” strategy for thwarting the highly lethal Ebola virus.
By Bill Snyder
August 15, 2016

In search of new asthma therapies

A peptide molecule relaxes airway smooth muscle and may be a potential therapeutic for asthma that has become resistant to standard therapies.
By Leigh MacMillan
August 12, 2016

New culprit in nerve degeneration

Vanderbilt researchers have discovered that regulation of cell volume plays a role in nerve degeneration and peripheral neuropathies.
By Leigh MacMillan
August 11, 2016

Research team takes aim at Ebola virus ‘decoy protein’

Using an antibody generated at Vanderbilt University Medical Center that neutralizes the Ebola virus, researchers at the Scripps Research Institute in La Jolla, California, have determined the structure of a “decoy” protein that may enable the virus to evade detection by the immune system.
By Bill Snyder
August 11, 2016

Study explores low oxygen’s impact on antibody quality

Hypoxia (lack of enough oxygen) is bad for the body as a whole, but in the neighborhood where infection-fighting antibodies arise, may be important for keeping proper order.
By Bill Snyder
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