Research

From left, Sheila Collins, PhD, Ryan Ceddia, PhD, and Heidi Hamm, PhD, and their colleagues have identified a potential new approach to reducing the global impact of obesity and diabetes. (photo by Erin O. Smith)

Releasing a brake that drives obesity and diabetes

Vanderbilt researchers have uncovered a potential new way to help curb the rapidly rising worldwide prevalence of metabolic disorders, including obesity and diabetes.

Update: Dame Frances Ashcroft to deliver Sept. 14 Vanderbilt Prize Lecture

Renowned diabetes expert Professor Dame Frances Ashcroft, recipient of the 2023 Vanderbilt Prize in Biomedical Science, will deliver her Vanderbilt Prize Discovery Lecture at 4 p.m. Thursday, Sept. 14, in 208 Light Hall.

Heather Pua, MD, PhD, and Neil Sprenkle, PhD, have discovered a protective role for microRNAs in immune cell macrophages during obesity, potentially opening new therapeutic avenues.

MicroRNAs in immune cells help protect against metabolic defects in obesity: study

Vanderbilt researchers have demonstrated that a cluster of microRNAs — small pieces of RNA that regulate gene expression — work in a type of immune cells called macrophages to help protect against metabolic defects in obesity.

Houra Merrikh and Juan Carvajal-Garcia, PhD, are studying how to prevent cancer therapy resistance. (photo by Erin O. Smith)

Foundation funds research to block drug resistance in cancer treatment

The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has funded an ambitious initiative to overcome one of the most perplexing and frustrating mysteries of cancer treatment — how to prevent drug resistance.

New reference tool supports replication of DNA biobank studies

Vanderbilt researchers created a phenotype-genotype reference map to assess data quality in DNA biobanks.

Predicting postop opioid use

VUMC study finds that preoperative patient characteristics can predict daily opioid use at six months after surgery, suggesting opportunities for development of electronic risk-stratification algorithms.

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