Research

July 28, 2022

Study reveals need for matching targeted therapies with EGFR subtypes

A Vanderbilt study suggests that clinicians should take a deeper dive into distinguishing EGFR mutations when prescribing targeted therapies for non-small-cell lung cancers.

By Tom Wilemon
Anna Means, PhD, R. Daniel Beauchamp, MD, and colleagues are studying a group of proteins that are essential to the growth of colorectal cancer tumors.
July 21, 2022

Researchers find potential new target against colorectal cancer

By Bill Snyder
A clinical trial supports approval of a new medication to treat moderate-to-severe asthma in children.
July 21, 2022

Study explores role RSV plays in later asthma development

A Vanderbilt clinical project will follow 1,950 Middle Tennessee children to determine how genes and the environment interact with RSV infection during the first year of life and contribute to asthma development

By Leah Mann
woman rubbing her throat
July 21, 2022

Difficulty swallowing linked to chronic opioid use: study

Vanderbilt researchers found that chronic use of opioid painkillers like hydrocodone and oxycodone significantly increases the risk of dysphagia, or difficulty swallowing.

By Bill Snyder
The study team included (front row, from left) Kelsey Voss, PhD, Rachel Bonami, PhD, Erin Wilfong, MD, PhD, (back row, from left) Jonathan Irish, PhD, Jeff Rathmell, PhD, and Ivelin Georgiev, PhD.
July 20, 2022

Vanderbilt team tracks cellular and antibody responses to COVID-19 vaccine

In a technical tour de force, a collaborative team of Vanderbilt researchers has characterized the antigen-specific immune response to the Pfizer SARS-CoV-2 RNA vaccine.

By Leigh MacMillan
July 15, 2022

Holowatyj named chair of scientific advisory board for ACPMP Research Foundation

Vanderbilt’s Andreana Holowatyj, PhD, MSCI, has been named the inaugural chair of the scientific advisory board for the Appendix Cancer Pseudomyxoma Peritonei Research Foundation.

By Tom Wilemon
July 13, 2022

Grad student Shelton selected as Vanderbilt Prize Student Scholar

Catherine Shelton has been selected as the 2022 Vanderbilt Prize Student Scholar.
By Bill Snyder
July 12, 2022

Probing the tumor microenvironment

Vanderbilt researchers used single-cell sequencing, imaging, and computational approaches to characterize the colonic tumor microenvironment, providing important insights to the components that play roles in colorectal tumor pathogenesis.
By Leigh MacMillan
July 11, 2022

A speedier treatment for depression?

Vanderbilt researchers used a computer-based search to identify a compound with promise as a new, mechanistically distinct and rapid-acting therapy for major depressive disorder.
By Paul Govern
July 7, 2022

Preempting sudden cardiac death

A technique to characterize all variants in genes associated with arrhythmia could improve the ability to identify and preemptively treat individuals at risk for sudden cardiac death.
By Bill Snyder
July 7, 2022

Professionalism and patient outcomes

A study of more than 70,000 trauma patients found that those who received care from a service with a high proportion of physicians modeling unprofessional behavior were at a 24% increased risk of death or complications.
By Paul Govern
July 6, 2022

Study shows two vaccine doses for mothers eases COVID complications for infants

Infants younger than 6 months were better protected from COVID-19 complications when mothers received two doses of the vaccine while pregnant, according to Vanderbilt researchers.
By Jessica Pasley
June 23, 2022

Study reveals how gastric cancer forms, suggests preventive treatment

Eunyoung Choi, PhD, assistant professor of Surgery, and colleagues identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cells are a key source of clonal evolution of dysplasia to multiple types of gastric cancer.
By Tom Wilemon