Autoantibodies against the p53 tumor suppressor protein may be a novel biomarker for identifying people, especially African Americans, at high risk for lung cancer.

Impairments in brain executive function happen earlier than motor symptoms in people with the gene mutation that causes Huntington disease, suggesting younger ages and cognitive symptoms be considered for any future clinical trials.

VUMC researchers have linked microRNAs with systemic lipid peroxidation, a discovery that could point to new therapeutic targets for a variety of diseases.

Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney.

John H. Exton, MBChB, MD, PhD, professor of Molecular Physiology and Biophysics, emeritus at Vanderbilt University, whose research provided fundamental insights into how many biologically active compounds control cellular physiology, died Dec. 18. He was 89.

Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury.