Research

June 7, 2022

Pediatric acute care use by ZIP code

Children with complex chronic conditions who live in low opportunity areas utilize more acute care and could benefit from hospital- and community-based interventions aimed at improving child health outcomes.

By Leigh MacMillan
June 6, 2022

Tracking the aging brain

The macrostructure — volume, area and length — of the brain’s white matter is useful for studying aging and could be a sensitive marker for neurodegenerative disorders such as Alzheimer’s disease, Vanderbilt researchers reported.

By Joshua Baker
June 3, 2022

Food allergy linked to lower risk of SARS-CoV-2 infection

By Nancy Humphrey
June 2, 2022

Sex & race & door-to-ECG time

More than a third of patients presenting at the emergency department with a suspected heart attack have a “delayed” ECG measure of heart function, with Black patients, females and non-English speakers more likely to experience delays.

By Paul Govern
June 2, 2022

Bacterial battle in 3D

Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.

By Bill Snyder
May 24, 2022

Diabetes, cardiovascular drug targets

Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Leigh MacMillan
May 23, 2022

Pushing (anti-overdose) drugs

An automated alert to encourage clinicians to coprescribe naloxone for patients at risk of opioid overdose increased naloxone prescriptions per opioid prescription 16-fold.
By Paul Govern
May 19, 2022

Genetics and blood pressure

Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension.
By Leigh MacMillan
May 19, 2022

A clue to an adverse drug event in children

Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.
By Joshua Baker
May 19, 2022

Molecular ‘switch’ may illuminate stomach disorders

An international team that included researchers from Vanderbilt University Medical Center has discovered a molecular switch that induces rapid proliferation of zymogen granule-secreting chief cells in the stomach to regenerate damaged tissue.
By Bill Snyder
May 17, 2022

Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency

A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.
By Leigh MacMillan
May 12, 2022

Study sheds light on the dark side of obesity

Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity.
By Bill Snyder
May 12, 2022

VUMC-led study finds Moderna COVID vaccine safe and effective for children

By Bill Snyder