Research Archive — Page 54 of 134

September 8, 2022

Immune cells drive beta cell loss in Type 2 diabetes

Vanderbilt researchers have discovered details of pancreatic beta cell loss — and potential therapeutic targets — during conditions of overnutrition, as occurs in obesity.

Luc Van Kaer, PhD, left, Luke Postoak and colleagues have identified a protein that is key to the “education” of immature T cells in the thymus.
September 1, 2022

Study identifies key player in T cell “education”

New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output.

Eunyoung Choi, PhD, James Goldenring, MD, PhD, and colleagues are studying the development of cancer in the stomach and esophagus.
September 1, 2022

Grant supports research to study gastric cancer origins

Vanderbilt researchers have received $5 million in funding from a new initiative by the National Cancer Institute that aims to define how gastric and gastroesophageal junction adenocarcinomas form and evolve at the cellular level.

August 30, 2022

A new mechanism for lupus

Vanderbilt researchers describe a new mechanism for the most common form of lupus and suggest a new treatment approach to this autoimmune disease.

August 29, 2022

Blood cancer progression

Vanderbilt researchers used single-cell technologies to explore the accumulation of mutations during blood cancer progression, which could help identify strategies for preventing leukemia before it occurs.

VUMC’s new automated biobanking system can store as many as 10 million biospecimens.
August 25, 2022

New high-tech biobank safeguards critical specimens