Research Archive — Page 56 of 133
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June 2, 2022
Bacterial battle in 3D
Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing. -
May 24, 2022
Diabetes, cardiovascular drug targets
Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered. -
May 23, 2022
Pushing (anti-overdose) drugs
An automated alert to encourage clinicians to coprescribe naloxone for patients at risk of opioid overdose increased naloxone prescriptions per opioid prescription 16-fold. -
May 19, 2022
Genetics and blood pressure
Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension. -
May 19, 2022
A clue to an adverse drug event in children
Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone. -
May 19, 2022
Molecular ‘switch’ may illuminate stomach disorders
An international team that included researchers from Vanderbilt University Medical Center has discovered a molecular switch that induces rapid proliferation of zymogen granule-secreting chief cells in the stomach to regenerate damaged tissue. -
May 17, 2022
Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency
A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.