Research

June 9, 2020

Vanderbilt, AstraZeneca collaborate on new COVID-19 antibody research

After evaluating the ability of more than 1,500 monoclonal antibodies to bind and neutralize the COVID-19 virus, SARS-CoV-2, in the laboratory, AstraZeneca signed an exclusive license to six candidate antibodies in Vanderbilt’s portfolio.

By Bill Snyder
June 9, 2020

Staph’s activation of blood clotting

Staph bacteria may change the factor they use to activate blood clotting — to evade the immune response — a new study suggests.

By Leigh MacMillan
June 8, 2020

When rankings are unfounded

There are many good reasons to survey anesthesiology patient satisfaction but ranking individual clinicians isn’t one of them, the authors of a new study conclude.

By Paul Govern
June 4, 2020

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

By Leigh MacMillan
June 4, 2020

Potential new cancer target

Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis.

By Bill Snyder
June 4, 2020

Remdesivir helps reduce COVID-19 recovery time: study

The investigational antiviral drug remdesivir can shorten the time to recovery in adults hospitalized with COVID-19, according to preliminary results of a clinical trial published last month in The New England Journal of Medicine.

By Bill Snyder
June 3, 2020

Study explores how staph bacteria can survive in bone

A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment.
By Leigh MacMillan
May 27, 2020

Darby lands award for research on complex human behaviors

For outstanding contributions to research in behavioral neurology, Ryan Darby, MD, assistant professor of Neurology, has won the 2020 Norman Geschwind Prize in Behavioral Neurology from the American Academy of Neurology (AAN).
By Paul Govern
May 27, 2020

Target trials support drug safety in pregnant patients

Out of concern for fetal safety, pregnant people have typically been excluded from drug trials. And when human health is on the line, drug studies assessing fetal safety in animal models may be viewed as far from definitive.
By Paul Govern
May 21, 2020

VUMC research ramps up in COVID-19 transition

As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at Vanderbilt University Medical Center.
By Bill Snyder
May 21, 2020

Team uses imaging to study ways the heart is affected by coronavirus

Researchers are using imaging and diagnostic pathology to examine postmortem hearts donated by victims of COVID-19 to gain a better understanding of how the coronavirus that causes COVID-19 affects the heart.
By Leigh MacMillan
May 19, 2020

VUMC Research Enterprise begins ramping up

As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at Vanderbilt University Medical Center.
By Bill Snyder
May 19, 2020

Probing innate immunity

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.
By Leigh MacMillan
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