Research Archive — Page 68 of 139

Colorized scanning electron micrograph showing magenta MRSA bacteria clustered around and interacting with a purple human neutrophil against a black background.
January 27, 2022

Impaired neutrophils in autoimmunity

Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity.

By Leigh MacMillan
(iStock)
January 20, 2022

New method enhances efforts to identify drug repurposing targets

Researchers at Vanderbilt University Medical Center have developed a new method for identifying drugs for the repurposing trials that can lead to new indications for drugs already in use.

By Paul Govern
Green-gloved laboratory worker holds two small tubes containing clear liquid over a blurred lab coat.
January 20, 2022

Omicron evades some but not all monoclonal antibodies: study

A new study found that several, but not all, of the human monoclonal antibodies used clinically to prevent patients from becoming severely ill from COVID-19 may not be protective against the Omicron variant now sweeping across the United States.

By Bill Snyder
From left, J.Court Reese, Stephanie Moore-Lotridge, PhD, Breanne Gibson, PhD, and Jonathan Schoenecker, MD, PhD, are discovering ways to prevent adverse outcomes in orthopaedic surgery.
January 19, 2022

Study identifies molecular trigger of severe injury-induced inflammatory response

Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure.

By Leigh MacMillan
VUMC NEWS logo in white lettering inside a cyan and yellow outlined square on a blue gradient background.
January 19, 2022

Clinical score can guide PRRT therapy decisions for neuroendocrine tumors

A clinical score system developed by researchers at Vanderbilt-Ingram Cancer Center (VICC) has been validated that can guide peptide receptor radionuclide therapy treatment decisions.

By Tom Wilemon
Healthcare professional in blue scrubs holding a tablet, overlaid with glowing digital medical interface graphics including a heart-monitor waveform, hearts, lungs, and connected data points.
January 18, 2022

Ensuring the “best possible” medication history

About 80% of hospital admission electronic records were missing a drug prescribed to an older adult, Vanderbilt researchers found, highlighting the need for a multipronged approach to address medication discrepancies and support safe prescribing practices.

By Bill Snyder