Research

close up of blood vessels
October 15, 2020

Brain blood vessel response to hypoxia

The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered.

By Leigh MacMillan
James Crowe Jr., MD, and colleagues are exploring how the body’s immune system gears up to fight off infection.
October 13, 2020

COVID-19 long-acting antibodies discovered by Vanderbilt University Medical Center move to phase 3 clinical trials

AstraZeneca is advancing into phase 3 clinical trials with an investigational COVID-19 therapy of two long-acting antibodies discovered by Vanderbilt University Medical Center and optimized by AstraZeneca.

By Bill Snyder
Michelle Southard-Smith, PhD, Aaron May-Zhang, PhD, and colleagues have created a molecular ‘atlas’ of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract.
October 8, 2020

Researchers create molecular ‘atlas’ of GI tract neurons

Researchers at Vanderbilt University Medical Center have generated the first comprehensive molecular “atlas” of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract.

By Bill Snyder
October 7, 2020

Vanderbilt Prize winner Doudna awarded Nobel Prize in Chemistry

University of California, Berkeley, biochemist Jennifer Doudna, PhD, recipient of the 2020 Vanderbilt Prize in Biomedical Science, has been awarded the 2020 Nobel Prize in Chemistry.

By Bill Snyder
October 6, 2020

Bick receives NIH Director’s Early Independence Award

Alexander Bick, MD, PhD, a new faculty member in the Division of Genetic Medicine at Vanderbilt University Medical Center, has received a 2020 National Institutes of Health (NIH) Director’s Early Independence Award.

By Bill Snyder
October 6, 2020

Early steps in reovirus replication

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.

By Leigh MacMillan
October 5, 2020

Treating appendicitis with antibiotics instead of surgery may be good option for some, but not all, patients

Antibiotics instead of surgery may be a good choice for some, but not all, patients with appendicitis, according to results from a study reported today in the New England Journal of Medicine.
By Nancy Humphrey
October 5, 2020

Nominations sought for 2021 Vanderbilt Prize in Biomedical Science

Nominations for the 2021 Vanderbilt Prize in Biomedical Science are now being accepted. The nomination deadline is Dec. 11.
By Bill Snyder
October 5, 2020

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.
By Sarah E. Glass
October 1, 2020

Pinpointing brain changes in psychosis

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment.
By Leigh MacMillan
October 1, 2020

Genes spell penicillin allergy risk

Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction.
By Paul Govern
September 24, 2020

Cohen Fund bolsters Siciliano’s memory research

Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medicine, has been selected to receive a one-year, $100,000 research award from the Stanley Cohen Innovation Fund to support his studies of the neural substrates of memory.
By Bill Snyder
September 22, 2020

Rational vaccine design

Understanding immunity generated by smallpox vaccine may hold lessons for COVID-19 vaccine development.
By Leigh MacMillan
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