Research Archive — Page 74 of 139

Head-and-shoulders portrait of a smiling man wearing a white medical coat and patterned tie against a brown background.
September 2, 2021

Study shows gene-drug interactions are common

When a drug or combination of drugs causes different responses in different people, genetic variation is often at play. Pharmacogenomics, through discovery of genetic risk and use of clinical genotyping, aims to reduce trial-and-error approaches to drug prescribing.

VUMC NEWS logo in white lettering inside a cyan and yellow outlined square on a blue gradient background.
August 26, 2021

Obese children, young adults at higher risk for thyroid cancer

Children and young adults who are obese are at greater risk for malignant thyroid nodules, according to new study from Monroe Carell Jr. Children’s Hospital at Vanderbilt.

Illustration of purple, textured spherical particles floating against a deep blue background, with bright rays radiating from several larger particles.
August 24, 2021

Autoimmunity advance

Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

Older woman with short white hair sits indoors with her hands clasped beneath her chin, looking pensively to the side.
August 23, 2021

Estrogen, depression and menopause

A shift in emotional processing may help women adapt to lower estrogen after menopause —unless they have a history of major depressive disorder, Vanderbilt researchers have found.

Green-gloved laboratory worker holds two small tubes containing clear liquid over a blurred lab coat.
August 20, 2021

COVID-19 antibody ‘cocktail’ discovered at VUMC protects chronically ill: study

A monoclonal antibody cocktail against the COVID-19 virus discovered at Vanderbilt University Medical Center and developed by AstraZeneca reduced the risk of symptoms in a study of immunocompromised and chronically ill adults later exposed to the virus by 77%, the company announced today.

Medical illustration of a blood vessel narrowing from fatty plaque buildup, with red blood cells in the bloodstream and enlarged spherical particles in the foreground.
August 19, 2021

Potential protection from atherosclerosis

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.