Research

June 25, 2024

International trial introduces another curative option for sickle cell disease 

The therapy, haploidentical bone marrow transplant with thiotepa and posttransplant cyclophosphamide, is as safe and more affordable than the recently FDA-approved myeloablative gene therapy and gene editing treatments.

By Jessica Pasley
June 25, 2024

Gene variant may underlie diabetes disparities: study

The study was the largest ancestry-stratified, genetic estimation of the heritability of diabetic retinopathy conducted to date and included an unprecedented number of individuals of non-Hispanic African ancestry — more than 46,000.

By Bill Snyder
June 24, 2024

Automated algorithm predicts risk of blood clots in hospitalized patients

This new entry to the field works in the background to provide real-time risk assessments, with no manual inputs from health care providers required.

By Paul Govern
Cathy Eng, MD
June 21, 2024

International overview of colorectal cancer provides multidisciplinary perspective of clinical advances

The authors hope the report will provide insight on the importance of education, screening and awareness to all health care providers.

By Tom Wilemon
June 21, 2024

Salmonella bacteria ‘steal’ nutrients from gut’s resident microbes

The discovery could point to novel strategies for treating food poisoning and other types of gastroenteritis.

By Leigh MacMillan
(iStock)
June 19, 2024

Study of messenger RNA regulatory mechanism reveals cancer risk genes

The Vanderbilt study used RNA-sequencing data generated in multiple normal tissues, along with matched genotype data from the Genotype-Tissue Expression Project as well as large-scale genomic data for cancers of the breast, ovary, prostate, colorectum, lung and pancreas.

By Tom Wilemon
June 18, 2024

Study tallies reports of unprofessional behavior among physicians

Reports from 193 hospitals were analyzed. It turns out that surgeons draw the most complaints.
By Paul Govern
June 14, 2024

Removing race improves accuracy of lung function testing in children

The study suggests the adjustment for race in spirometry resulted in an underreporting — and thus possibly undertreatment — of chronic lung diseases, including asthma and cystic fibrosis, in Black children.
By Bill Snyder
June 13, 2024

Study shows transplant volumes decreased, costs rose following federal policy change

The new policy changed liver allocations from a regional service area to an “acuity circles” system that assigns donor livers as far as 500 nautical miles away based on the acuity of recipients.
By Matt Batcheldor
June 13, 2024

Multicenter study identifies method of preoxygenation that prevents hypoxemia and cardiac arrest during emergency tracheal intubation

Preoxygenation is the administration of supplemental oxygen prior to the start of a procedure to increase the content of oxygen in the lung and decrease the risk of hypoxemia
By Nancy Humphrey
June 12, 2024

Scientists find antibodies that block parainfluenza virus infection

The antibodies may have clinical benefit as antiviral drugs to treat potentially life-threatening infections in elderly and immunosuppressed patients.
By Bill Snyder
June 12, 2024

Obesity-cancer connection discovery suggests strategies for improving immunotherapy 

The study reported in the journal Nature provides a mechanistic explanation for the “obesity paradox” — that obesity can contribute to cancer progression but also improve response to immunotherapy.
By Leigh MacMillan
June 12, 2024

Study shows a simple blood test can predict cardiorespiratory fitness

The researchers tested the feasibility of using a simple set of proteins from blood to capture a molecular fingerprint of cardiorespiratory fitness.
By Matt Batcheldor
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