Paul Govern

Lisa Bastarache, MS, Josh Denny, MD, MS, and colleagues are helping researchers study associations among de-identified genotype data and electronic health records data. (photo by John Russell)

PheWAS Core helps researchers make sense of electronic health record data

Some biomedical researchers may be unsure about routine electronic health record (EHR) data and how useful it ultimately may prove for drawing meaningful, actionable associations that warrant changes to clinical practice and lead to improved clinical outcomes.

Study explores genetic risk for suicide attempt

Using data from the UK Biobank and Vanderbilt’s BioVU, a new study in the journal Molecular Psychiatry finds that approximately 4 percent of suicide attempt risk is captured by genotype data.

Study finds patient messages help predict medication adherence

Around two-thirds of patients treated for breast cancer will have had hormone-sensitive tumors and, after their initial treatment, will be advised to undergo hormone therapy for five to 10 years to prevent recurrence.

Study tracks repercussions from reduced pre-op testing

When clinical teams at Vanderbilt University Medical Center dramatically reduced several types of preoperative testing for elective surgery patients, there were no repercussions for these patients in terms of case cancellation rates, average length of stay in the hospital or rates of readmission to VUMC.

Clinical Data Research Network primed for growth

The Mid-South Clinical Data Research Network, led by Vanderbilt University Medical Center’s Russell Rothman, MD, MPP, is a collaborative effort among a group of large health care systems to support and conduct innovative comparative effectiveness research and clinical trials.

Study uses IT to prevent early childhood obesity

A research team led by Vanderbilt University Medical Center’s Russell Rothman, MD, MPP, has been approved for a $7 million research funding award from the Patient-Centered Outcomes Research Institute (PCORI) to conduct a randomized, multi-center trial comparing clinic and consumer information technology approaches to promote healthy behaviors and prevent early childhood obesity.

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