Leigh MacMillan

Ayaka Sugiura and Jeff Rathmell, PhD, are studying a metabolic enzyme involved in T cell function that may offer a new target for anti-inflammatory therapeutics.
November 11, 2021

CRISPR screen identifies new anti-inflammatory drug target

A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics.

By Leigh MacMillan
Roy Zent, MBBCh, PhD, left, Fabian Bock, MD, PhD, and colleagues are studying the factors involved in the maintenance and integrity of the kidney collecting duct.
November 4, 2021

Harrison Society researcher discovers key regulator of kidney cell structure

New research from Vanderbilt could aid efforts to promote kidney regeneration after injury or to develop engineered organs.

By Leigh MacMillan
November 2, 2021

Shifts in neuroendocrine cancer clinical trial design

Clinical trials that focus on specific types of neuroendocrine neoplasms — heterogeneous tumors that can occur anywhere in the body — will be more likely to enhance drug development for these tumors, Vanderbilt physicians assert.

By Leigh MacMillan
November 1, 2021

Breast cancer survivors: eat nuts

Breast cancer survivors who reported eating nuts regularly had 50% reduced risk of breast cancer recurrence, metastasis or mortality, Vanderbilt epidemiologists found in Shanghai Breast Cancer Survival Study.

By Leigh MacMillan
October 28, 2021

Pancreatic beta-cell booster

Blocking inflammatory signaling improves beta-cell characteristics in a mouse model of type 2 diabetes and may provide added benefits to GLP-1R diabetes medications.

By Leigh MacMillan
October 21, 2021

Study links genetic variants, protein expression and human diseases

An international research team has developed a new resource that connects genetic variants and protein expression, which is expected to speed the identification of genes that cause disease — and point to novel treatment strategies.

By Leigh MacMillan
October 19, 2021

Combo therapy slows prostate cancer

A new combination treatment showed promise in slowing the growth of castration-resistant prostate cancer in animal models, Vanderbilt researchers discovered.
By Leigh MacMillan
October 18, 2021

Berlin Institute of Health’s Eils set for next Discovery Lecture

Roland Eils, PhD, will discuss efforts to translate the deluge of genomics data generated by international initiatives into understanding disease mechanisms during the next web-based Discovery Lecture.
By Leigh MacMillan
October 18, 2021

Mental health screening in epilepsy

Sending survey tools to epilepsy patients before their clinic appointment doubled the numbers of patients who were diagnosed and treated for depression and anxiety disorders, Vanderbilt neurologists found.
By Leigh MacMillan
October 4, 2021

Neurologic complications of the flu

Neurologic complications are common in children hospitalized with influenza, especially those with chronic neurologic conditions, and are associated with worse outcomes.
By Leigh MacMillan
September 30, 2021

Molecular imaging of C. diff infection

C. difficile — the leading cause of hospital-associated intestinal infections — induces a rapid influx of bile acids into the gut, which could provide a novel target for blocking infection.
By Leigh MacMillan
September 20, 2021

Brain circuits in schizophrenia

Vanderbilt psychiatrists are probing brain circuit hyperactivity implicated in schizophrenia, with the idea that normalizing the hyperactivity may improve cognitive processes.
By Leigh MacMillan
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