Leigh MacMillan

Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

Pathways of radiosensitization

Austin Kirschner and colleagues demonstrate how a hormone therapy for prostate cancer improves radiation’s tumor-killing power.

bacteria microbiome

How bugs overcome host defenses

Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”

Harvard’s Gaziano set for April 11 clinical pharmacology lecture

J. Michael Gaziano, MD, MPH, an internationally recognized chronic disease epidemiologist, will deliver the 15th annual Grant R. Wilkinson Distinguished Lectureship in Clinical Pharmacology on Thursday, April 11.

Cardiac dysfunction in DMD

The protein MMP7 is elevated in blood from patients with Duchenne muscular dystrophy who have cardiac dysfunction, suggesting that it may be a biomarker for heart disease severity.

Drug interaction causes hypotension

A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

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