Leigh MacMillan

Brain-gut connection in autism

An association between rigid-compulsive behaviors and gastrointestinal symptoms in autism spectrum disorder may point to a common biological pathway that impacts both the brain and the gut.

Cancer cells combine tools to increase invasiveness

Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered.

Targeting tumor “supply lines”

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies.

Cancer drug enhances cognition

The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women.

Manager of mitotic stress

The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis.

Therapeutic target for gastric cancer

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.

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