Leigh MacMillan

April 17, 2013

‘Longevity’ gene aids kidney survival

A gene associated with cell survival and longevity may protect the kidney from acute injury.

By Leigh MacMillan
April 15, 2013

A role for blood vessels in delirium?

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

By Leigh MacMillan
April 12, 2013

Lung damage protector

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

By Leigh MacMillan
April 11, 2013

Leukemia culprit’s cellular actions

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

By Leigh MacMillan
April 4, 2013

Nobel laureate Hartwell set for Discovery Lecture

Nobel laureate Lee Hartwell, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, April 11.

By Leigh MacMillan
April 3, 2013

“Silent” B cells trigger autoimmunity

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

By Leigh MacMillan
April 1, 2013

Fingers and toes: joint forming factor

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.
By Leigh MacMillan
March 29, 2013

Plant compound stops colon cancer cells

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.
By Leigh MacMillan
March 28, 2013

Oxford’s Collins set for Discovery Lecture

Sir Rory Collins, MB BS, professor of Medicine and Epidemiology at the University of Oxford, England, will deliver the next Flexner Discovery Lecture on Thursday, April 4.
By Leigh MacMillan
March 28, 2013

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.
By Leigh MacMillan
March 20, 2013

New drugs a good BET for brain cancer

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.
By Leigh MacMillan
March 18, 2013

IRF6 on the tip of tongue development

The factor IRF6 plays important roles in the development of the tongue.
By Leigh MacMillan
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