A coronavirus protein is required for replication of the viral genome and may be a good treatment target for SARS and other diseases caused by coronaviruses.

A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

Alkaline phosphatase enzymes appear to play roles in promoting pregnancy and in protecting the uterus from bacterial infection.

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments.

In an effort to understand how neurons develop different “architectures,” Vanderbilt developmental biologists have discovered a genetic switch that controls one type of neuron branching in the nematode worm.