Aliquots - Research Briefs

July 28, 2022

Specialty pharmacists help reduce MS relapse risk

Just one-third of patients with relapsing multiple sclerosis remain on disease-modifying therapy, and specialty pharmacists are in a unique position to help coordinate therapy discontinuation or change and reduce the risk of relapse.

By Joshua Baker
July 12, 2022

Probing the tumor microenvironment

Vanderbilt researchers used single-cell sequencing, imaging, and computational approaches to characterize the colonic tumor microenvironment, providing important insights to the components that play roles in colorectal tumor pathogenesis.

By Leigh MacMillan
July 11, 2022

A speedier treatment for depression?

Vanderbilt researchers used a computer-based search to identify a compound with promise as a new, mechanistically distinct and rapid-acting therapy for major depressive disorder.

By Paul Govern
July 7, 2022

Preempting sudden cardiac death

A technique to characterize all variants in genes associated with arrhythmia could improve the ability to identify and preemptively treat individuals at risk for sudden cardiac death.

By Bill Snyder
July 7, 2022

Professionalism and patient outcomes

A study of more than 70,000 trauma patients found that those who received care from a service with a high proportion of physicians modeling unprofessional behavior were at a 24% increased risk of death or complications.

By Paul Govern
June 21, 2022

Evaluation of hearing brochures

Most brochures given to parents about newborn hearing screening results need to be modified to make them more understandable, Vanderbilt hearing researchers found.

By Emily Stembridge
June 20, 2022

Ginseng intake and mortality

Regular ginseng intake, particularly over a long duration, is associated with decreased risk of death from all causes, Vanderbilt researchers discovered in a large epidemiological study.
By Leigh MacMillan
June 16, 2022

BMI genetics influence heart function

Vanderbilt researchers have discovered that a genetic predisposition to elevated body mass index increases the risk of diastolic dysfunction — a cardiac condition that can lead to heart failure.
By Leigh MacMillan
June 16, 2022

Breast cancer biomarkers of response

Vanderbilt researchers have identified blood-based biomarkers associated with complete responses to neoadjuvant chemotherapy in patients with breast cancer.
By Joshua Baker
June 7, 2022

Pediatric acute care use by ZIP code

Children with complex chronic conditions who live in low opportunity areas utilize more acute care and could benefit from hospital- and community-based interventions aimed at improving child health outcomes.
By Leigh MacMillan
June 6, 2022

Tracking the aging brain

The macrostructure — volume, area and length — of the brain’s white matter is useful for studying aging and could be a sensitive marker for neurodegenerative disorders such as Alzheimer’s disease, Vanderbilt researchers reported.
By Joshua Baker
June 2, 2022

Sex & race & door-to-ECG time

More than a third of patients presenting at the emergency department with a suspected heart attack have a “delayed” ECG measure of heart function, with Black patients, females and non-English speakers more likely to experience delays.
By Paul Govern
June 2, 2022

Bacterial battle in 3D

Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.
By Bill Snyder