Aliquots - Research Briefs

December 18, 2023

Study examines social factors and cardiovascular disease risk

Eight social factors were among the top 15 markers of cardiovascular disease risk and could help guide community prevention efforts, according to a new study using machine learning algorithms.

By Paul Govern
December 8, 2023

You missed a few: a better way to count health care-associated influenza cases

The traditional definition of health care-associated influenza leads to gross undercounting, a Vanderbilt study suggests.

By Paul Govern
December 6, 2023

Pasteurization reduces bioactive component of breast milk

Pasteurization of breast milk affects the concentration of osteopontin, a bioactive protein with roles in intestinal, immunological and brain development — suggesting that osteopontin supplementation should be considered when donor milk is provided to preterm infants.

By Leigh MacMillan
December 5, 2023

Role of immunity in kidney injury hints at a potential therapy: study

Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.

By Bill Snyder
November 21, 2023

Commensal gut bacterium protects from severe intestinal infection

The commensal bacterium Turicibacter sanguinis could be used to protect against severe intestinal infections, Vanderbilt researchers discovered.

By Leigh MacMillan
November 16, 2023

Nasty microbe H. pylori has Achilles’ heel

Vanderbilt researchers found that an H. pylori enzyme is essential for colonization of the stomach, suggesting it as a promising therapeutic target for H. pylori infection.

By Paul Govern
October 31, 2023

Polygenic “scores” may improve cancer screening

Accounting for genetic variability in biomarkers not associated with cancer risk could avoid unnecessary diagnostic procedures, Vanderbilt researchers found.
By Bill Snyder
September 14, 2023

Bone metabolism changes with aging

Vanderbilt researchers have detailed how aging alters the metabolism of bone-forming cells, which could contribute to age-related osteoporosis.
By Leigh MacMillan
September 7, 2023

Low-flow cerebrospinal fluid in Huntington’s disease: study

Vanderbilt researchers found reduced net flow of cerebrospinal fluid in Huntington’s disease, which could contribute to mutant protein retention and altered responsiveness to medications delivered via the spinal cord.
By Paul Govern
August 31, 2023

New reference tool supports replication of DNA biobank studies

Vanderbilt researchers created a phenotype-genotype reference map to assess data quality in DNA biobanks.
By Paul Govern
August 24, 2023

Predicting postop opioid use

VUMC study finds that preoperative patient characteristics can predict daily opioid use at six months after surgery, suggesting opportunities for development of electronic risk-stratification algorithms.
By Paul Govern
August 2, 2023

Personalizing treatment for sinus syndrome

Understanding the inflammatory characteristics of subtypes of chronic rhinosinusitis with polyps should assist with selection of effective therapies, Vanderbilt researchers report.
By Leigh MacMillan
July 25, 2023

Signaling pathways in liposarcomas

A broad bioinformatics approach revealed that Hedgehog signaling is upregulated in dedifferentiated liposarcoma, suggesting this pathway may be an early indicator of poor prognosis and a potential therapeutic target.
By Leigh MacMillan
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