Vanderbilt researchers found reduced net flow of cerebrospinal fluid in Huntington’s disease, which could contribute to mutant protein retention and altered responsiveness to medications delivered via the spinal cord.

Vanderbilt researchers created a phenotype-genotype reference map to assess data quality in DNA biobanks.

VUMC study finds that preoperative patient characteristics can predict daily opioid use at six months after surgery, suggesting opportunities for development of electronic risk-stratification algorithms.

Understanding the inflammatory characteristics of subtypes of chronic rhinosinusitis with polyps should assist with selection of effective therapies, Vanderbilt researchers report.

A broad bioinformatics approach revealed that Hedgehog signaling is upregulated in dedifferentiated liposarcoma, suggesting this pathway may be an early indicator of poor prognosis and a potential therapeutic target.

Vanderbilt researchers report on a musician who acquired synesthesia — a merging of sensations — and improved creativity following a traumatic brain injury.

A customizable framework uses simulated patients to distinguish effects of a new treatment from “learning effects” for clinicians; it should help identify training opportunities and hasten treatment improvements.