Vanderbilt researchers created a phenotype-genotype reference map to assess data quality in DNA biobanks.

VUMC study finds that preoperative patient characteristics can predict daily opioid use at six months after surgery, suggesting opportunities for development of electronic risk-stratification algorithms.

Understanding the inflammatory characteristics of subtypes of chronic rhinosinusitis with polyps should assist with selection of effective therapies, Vanderbilt researchers report.

A broad bioinformatics approach revealed that Hedgehog signaling is upregulated in dedifferentiated liposarcoma, suggesting this pathway may be an early indicator of poor prognosis and a potential therapeutic target.

Vanderbilt researchers report on a musician who acquired synesthesia — a merging of sensations — and improved creativity following a traumatic brain injury.

A customizable framework uses simulated patients to distinguish effects of a new treatment from “learning effects” for clinicians; it should help identify training opportunities and hasten treatment improvements.

A case study of a rare disorder uncovers roles for the protein dysbindin in the adaptive immune response and suggests that mutations may underlie some cases of very early onset inflammatory bowel disease.