Aliquots - Research Briefs

December 5, 2017

DNA damage repair: molecular insights

Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.

By VUMC News and Communications
December 1, 2017

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.

By VUMC News and Communications
tree roots
November 30, 2017

Lineage tracing in the gut

Vanderbilt investigators have developed an algorithm to classify cell types from experimental data, making it possible to understand how organs develop.

By Bill Snyder
November 15, 2017

Radiation and pulmonary fibrosis

To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response.

By Leigh MacMillan
November 13, 2017

Salt, inflammation and hypertension

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension.

By Leigh MacMillan
November 10, 2017

A lipid’s role in cell division

Lipids in the plasma membrane regulate the position of the contractile ring that is required for cell division, Vanderbilt researchers have discovered.

By Natalya Ortolano
November 9, 2017

HIV outreach and return to care

When chronic disease patients let their care lapse and fail to show for clinic appointments, it may behoove clinics to reach out and encourage a return to care.
By Paul Govern
November 1, 2017

Bioactive lipids and rheumatoid arthritis

An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease.
By Leigh MacMillan
October 30, 2017

Disparities in influenza outcomes

Neighborhood determinants – represented by census tract data – contribute to the risk of influenza hospitalization and could be used to guide interventions such as vaccinations to high-risk areas.
By Leigh MacMillan
October 27, 2017

Impulsivity in Parkinson’s Disease

A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans.
By Allyson Mallya
October 26, 2017

Gut response to fluid flow

Vanderbilt researchers have discovered that microvilli – finger-like projections from cells in the intestine – respond to the shear stress of fluid flow to drive a cellular pathway that regulates nutrient balance.
By VUMC News and Communications
October 18, 2017

Calcium intake and colorectal cancer

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.
By Leigh MacMillan
October 16, 2017

Gender, pain and dementia

Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease.
By Bill Snyder
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