Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease.

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies.

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas.

With other risk factors held equal, children who received a benzodiazepine sedative drug were nearly three times more likely to experience delirium – confused thought – the following day.

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.