Aliquots - Research Briefs

October 11, 2013

New target for stopping inflammation

Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.

By Bill Snyder
October 10, 2013

Probing mutant EGF receptor regulation

Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies.

By Leigh MacMillan
October 2, 2013

Early cell death in MS

Death of oligodendrocytes, the cells that make myelin, appears to be an early event in the development of multiple sclerosis.

By Leigh MacMillan
September 30, 2013

Gene interactions and cavities

Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay.

By Leigh MacMillan
September 27, 2013

Metabolic profiling of vision loss

A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis.

By Leigh MacMillan
Stomach
September 26, 2013

Cell changes en route to stomach cancer

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.

By Leigh MacMillan
September 18, 2013

Fishing for new anti-cancer drugs

Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.
By Leigh MacMillan
September 16, 2013

Mapping brain membrane proteins

New mass spectrometry imaging methods will enable studies of the distribution and identification of membrane proteins directly within tissues.
By Leigh MacMillan
September 13, 2013

Cancer nanomedicines on target

Therapeutic nanoparticles may offer a powerful new way to image and treat cancer at the same time.
By Leigh MacMillan
September 12, 2013

‘Proofreader’ key to coronavirus growth

A coronavirus protein is required for replication of the viral genome and may be a good treatment target for SARS and other diseases caused by coronaviruses.
By Leigh MacMillan
August 28, 2013

Probing intestinal immune cell roles

A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.
By Leigh MacMillan
August 26, 2013

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.
By Leigh MacMillan
August 23, 2013

Pregnancy promoter and protector

Alkaline phosphatase enzymes appear to play roles in promoting pregnancy and in protecting the uterus from bacterial infection.
By Leigh MacMillan
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