Therapeutic target for synovial sarcoma

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

Molecular circuits in ovarian cancer

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

Amish aid study of Parkinson genetics

Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles.

Defusing ‘C. diff’ infection

Neurotransmitter’s role in bone balance

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.

Preserving antibiotic arsenal for TB

Clinicians should be cautious about prescribing newer fluoroquinolone antibiotics to patients with TB risk factors; doing so may jeopardize the use of these agents against TB.