Using computational tools to search for the genetic basis of what makes us human, Vanderbilt Assistant Professor of Biomedical Informatics Tony Capra and colleagues at the University of California-San Francisco have identified promising candidate regions.

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles.

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.

Clinicians should be cautious about prescribing newer fluoroquinolone antibiotics to patients with TB risk factors; doing so may jeopardize the use of these agents against TB.