Health and Medicine

March 4, 2021

Targeting glucagon action in diabetes

Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy.

By Leigh MacMillan
March 4, 2021

Biostatistician DeMets set for next Discovery Lecture

David DeMets, PhD, known for his work on statistical methods to monitor interim clinical trial data for early evidence of benefit or harm, will deliver the next web-based Discovery Lecture.

By Leigh MacMillan
March 4, 2021

Chikungunya antibody identified at VUMC moves forward

Evotec, a drug company headquartered in Hamburg, Germany, has begun a phase 1 clinical trial of a monoclonal antibody against the chikungunya virus that was identified at Vanderbilt University Medical Center.

By Bill Snyder
February 25, 2021

Females with autism reach puberty earlier: study

Blythe Corbett, PhD, professor of Psychiatry and Behavioral Sciences and investigator with the Vanderbilt Kennedy Center, recently led a study which found that on average, females with autism spectrum disorder (ASD) experienced the onset of puberty 9.5 months earlier than their peers.

By Emily Stembridge
February 25, 2021

Case Western’s Jain to discuss age-related disorders at next Discovery Lecture

Mukesh Jain, MD, vice dean for Academic Affairs and Medical Sciences and professor of Medicine at Case Western Reserve University, will discuss the discovery of aging-related disease genes and pathways during the next web-based Discovery Lecture.

By Leigh MacMillan
February 23, 2021

Calcification after severe injury

Vanderbilt researchers have linked bone-related complications of severely injured patients — findings that could help minimize these complications.

By Emily Stembridge
February 22, 2021

MRI view of brain tumor prognosis

In patients with glioblastoma brain tumors, features detected on MRIs at diagnosis were associated with survival, Vanderbilt Medical Center investigators found.
By Leigh MacMillan
February 18, 2021

Genetic clues in eye birth defect

Sabine Fuhrmann and colleagues have discovered a novel underlying cause of coloboma — a birth defect that causes missing tissue in the eye and accounts for up to 10% of childhood blindness.
By Leigh MacMillan
February 18, 2021

Gene variant and glucose metabolism

Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.
By Leigh MacMillan
February 18, 2021

Research Staff Awards honor those who help drive engines of discovery

Laboratory and administrative personnel at Vanderbilt University Medical Center were honored last week for research excellence during the 17th annual Research Staff Awards, held virtually this year because of the pandemic.
By Bill Snyder
February 18, 2021

VUMC postdoctoral scientist named HHMI Hanna Gray Fellow

Valeria Reyes Ruiz, PhD, a postdoctoral fellow in the Department of Pathology, Microbiology and Immunology, has been selected as a 2020 Hanna Gray Fellow by the Howard Hughes Medical Institute (HHMI).
By Leigh MacMillan
February 11, 2021

Vanderbilt, Zambia researchers find delirium in hospitalized patients linked to mortality, disability in Sub-Saharan Africa

Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.
By Holly Fletcher
February 11, 2021

Grant supports speedy sorting of health records by phenotype

Wei-Qi Wei, MD, PhD, assistant professor of Biomedical Informatics and scientific director of the Precision Phenotyping Core at the Center for Precision Medicine, has been awarded a four-year, $1.7 million grant from the National Institutes of Health (grant GM139891) to continue
By Paul Govern
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