Treating depressed individuals and figuring out who will and won’t respond to antidepressants is mostly trial and error — much to the frustration of patients and the health care providers who treat them.

Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease.

Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine.

Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions.

Anti-cancer drugs are typically tested on one type of cancer at a time. But an international consortium of cancer investigators, including Vanderbilt-Ingram Cancer Center (VICC) researchers, simultaneously tested an existing therapy in patients with several different forms of cancer that all exhibit the same tumor gene mutation.

The Vanderbilt Institute for Global Health (VIGH) has received two new grants from the Fogarty International Center of the National Institutes of Health (NIH) to build HIV-focused research capacity with key partners in Zambia, Mozambique and Brazil.

Many women who receive chemotherapy for breast cancer report problems with their thinking, memory and attention after treatment.