New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

New studies explain how T-cell receptors use force to recognize and protect us against pathogens.

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

New findings explain why variation in a particular gene is the most important determinant of fasting blood glucose levels in humans.

A Vanderbilt University-led research team has discovered a molecular “rheostat” in the brain’s appetite control center that may provide new insights into obesity, which is at epidemic levels in this country.

Prospecting for genes that might be implicated in cancer, a Vanderbilt University Medical Center research team has struck pay dirt.