Research

February 11, 2020

A key to calcium signaling

Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.

By Sanjay Mishra
February 10, 2020

Imaging breast cancer cell size

A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

By Leigh MacMillan
February 6, 2020

Powering H. pylori pathogenesis

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.

By Leigh MacMillan
February 6, 2020

Antibody mixture may help block Ebola virus infection

A research team led by scientists at Vanderbilt University Medical Center has developed an antibody mixture that in animals is highly effective in blocking infection by the Ebola virus.

By Bill Snyder
February 6, 2020

Conn, Calipari to receive major pharmacology awards

Two Vanderbilt University pharmacologists have won prestigious awards from the American Society for Pharmacology and Experimental Therapeutics (ASPET).

By Bill Snyder
February 6, 2020

Team tracks integrin’s role in lung function

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered.

By Bill Snyder
February 6, 2020

New tool probes gene regulation

Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation.
By Leigh MacMillan
January 29, 2020

Protein research seeks to induce tumor regression

Understanding how MYC interacts with WDR5 and other cofactors could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks.
By Bill Snyder
January 28, 2020

Imaging nerve regeneration

Diffusion MRI may provide a noninvasive approach to assess nerve regeneration and distinguish successful from unsuccessful repairs earlier.
By Leigh MacMillan
January 27, 2020

A new contributor to atherosclerosis

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.
By Leigh MacMillan
January 23, 2020

Insights on diabetic retinopathy

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.
By Leigh MacMillan
January 23, 2020

HDL-cholesterol and breast cancer risk

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.
By Leigh MacMillan
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.
By Leigh MacMillan
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