Research Archive — Page 54 of 194

January 29, 2020

Protein research seeks to induce tumor regression

Understanding how MYC interacts with WDR5 and other cofactors could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks.

By Bill Snyder
Stylized illustration of glowing orange nerve cells with branching axons and interconnected fibers against a black background.
January 28, 2020

Imaging nerve regeneration

Diffusion MRI may provide a noninvasive approach to assess nerve regeneration and distinguish successful from unsuccessful repairs earlier.

By Leigh MacMillan
Illustration of an artery narrowed by yellow cholesterol plaque deposits, with red blood cells flowing through the remaining open channel.
January 27, 2020

A new contributor to atherosclerosis

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.

By Leigh MacMillan
January 23, 2020

Insights on diabetic retinopathy

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

By Leigh MacMillan
Illustration of red blood cells interspersed with smaller spherical cells in a dark red bloodstream.
January 23, 2020

HDL-cholesterol and breast cancer risk

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.

By Leigh MacMillan
Side-by-side fluorescent microscopy comparison: larger, regularly shaped healthy cartilage cells on the left and smaller, irregularly shaped cells in the CATIFA model on the right, labeled “Healthy Cartilage Cells” and “CATIFA model Cartilage Cells.”
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

By Leigh MacMillan