Research

June 22, 2023

Pathways to a healthy liver

Hepatic stellate cells maintain liver mass and function; the signaling factors they use could be exploited therapeutically to promote liver regeneration and inhibit cancerous proliferation, Vanderbilt researchers suggest.

By Bill Snyder
June 22, 2023

Mosaicism and genetic disease

Genetic mosaicism — when the body’s cells do not all have the same genetic makeup — could generate variants previously thought to be spontaneous in genetic disease, and detecting parental mosaicism could clarify recurrence risk for future children.

By Leigh MacMillan
Research assistant Mahsa Majedi loads reagent used in DNA sample preparation in the genomics lab. She is part of a team of more than a dozen people at VUMC who are “sprinting” to develop — within 90 days — an antibody-based treatment to stop the spread of the Zika virus.
June 22, 2023

VUMC, Oxford team develops ‘blueprint’ to block lethal virus

Researchers at Vanderbilt University Medical Center and the University of Oxford have determined how a human monoclonal antibody isolated at Vanderbilt in 2021 can prevent infection by the potentially lethal Sin Nombre virus.

By Bill Snyder
June 21, 2023

Vanderbilt launches $17 million program to advance diversity of research faculty

Vanderbilt University Medical Center and Vanderbilt University are launching a $17 million multiyear transformative program with support from the National Institutes of Health to accelerate diversity, equity, inclusion and belonging in the biomedical research community.

By Holly Fletcher
June 15, 2023

Early-onset CRC germline genetic differences identified by race, ethnicity

A Vanderbilt study that delved into genetic predisposition for early-onset colorectal cancer by race and ethnicity has identified differing germline risk variants.

By Tom Wilemon
June 14, 2023

NIH grant boosts international TB research consortium

A new grant will help support Vanderbilt’s RePORT Brazil, one of an international consortium’s six regional tuberculosis research programs.

By Paul Govern
June 13, 2023

Maternal diet influences postnatal diabetes risk

Studies in a primate animal model suggest that islet hyperfunction — which in humans is associated with increased fat mass and Type 2 diabetes — is programmed in offspring by a maternal Western-style diet during pregnancy.
By Bill Snyder
June 12, 2023

Images predict functional decline

MRI brain scans at baseline for study participants 60 and older — who were free of clinical dementia at study entry — predicted a decline in independent function five years later.
By Paul Govern
June 8, 2023

Targeting calcium handling in A-fib

The drug ent-verticilide reduced A-fib incidence and duration in an animal model, suggesting it may be a viable therapeutic option.
By Leigh MacMillan
June 8, 2023

An image of cancer treatment response

An MRI method developed by Vanderbilt researchers uses imaging data to derive cell size and could be added to clinical practice for better monitoring of breast cancer treatment response.
By Sarah E. Glass
June 8, 2023

Enhanced treatment helps fast nicotine metabolizers quit smoking

A study from Vanderbilt researchers has found that enhanced treatment support can help smokers who have more difficulty quitting because they are fast metabolizers of nicotine.
By Tom Wilemon
June 7, 2023

Byndloss selected for Burroughs Wellcome Fund infectious disease award

Vanderbilt's Mariana Byndloss, DVM, PhD, is one of eight Burroughs Wellcome Fund 2023 Investigators in the Pathogenesis of Infectious Disease.
By Leigh MacMillan
May 23, 2023

Treating kidney injury before it happens

Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.
By Sarah E. Glass
1 … 6 7 8 9 10 … 216