Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.

Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.

The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.

Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.

Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.

Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease.