antipsychotics

High-dose antipsychotics place children at increased risk of unexpected death

Children and young adults without psychosis who are prescribed high-dose antipsychotic medications are at increased risk of unexpected death, despite the availability of other medications to treat their conditions, according to a Vanderbilt University Medical Center study published today in JAMA Psychiatry.
Unexpected death includes deaths due to unintentional drug overdose or cardiovascular/metabolic causes.

Antipsychotics ineffective for treating ICU delirium: study

Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.