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Team explores transcription factor’s autoimmunity role

Increasing expression of a transcription factor called KLF2 can promote immunological self-tolerance and “tune down” autoimmunity, researchers at Vanderbilt University Medical Center reported recently.

“Silent” B cells trigger autoimmunity

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

How ‘Jedi’ disposes of dead neurons

The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.