Basic Sciences

September 27, 2018

Fat tissue’s “iron sink”

Alyssa Hasty and colleagues demonstrated that immune cells called macrophages act in fat tissue to store iron and prevent iron toxicity.

September 13, 2018

How microvilli form

A protein called IRTKS helps build the microvilli that form the border of cells in the intestines, explaining why the protein is a frequent target of gut pathogens.

September 6, 2018

Link between immune system, disease explored

The first Flexner Discovery Lecture of the academic year featured presentations by two Vanderbilt faculty members.

array of test tubes with pipette dropping fluid into one
September 5, 2018

Unleashing TIGER on small RNAs

Vanderbilt investigators have developed a new analytical tool to identify, quantify and analyze small RNAs.

August 30, 2018

A brain-builder called “Shh”

New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

August 30, 2018

Energetic gene switch

New findings link flux through glycolysis, which produces cellular energy, with transcription and gene expression via histone modification.