bioinformatics

Signaling pathways in liposarcomas

A broad bioinformatics approach revealed that Hedgehog signaling is upregulated in dedifferentiated liposarcoma, suggesting this pathway may be an early indicator of poor prognosis and a potential therapeutic target.

Paul Harris, PhD

Paul Harris named Vice President for Research Informatics

Paul Harris, PhD, has been appointed to a new role as Vice President for Research Informatics at Vanderbilt University Medical Center.

Initiative seeks to extract cancer phenotypes from electronic health records

The National Cancer Institute (NCI) has funded the development of interactive visual tools that will allow researchers to extract cancer phenotypes from electronic medical records.

collection of vintage pocket watches

Study reveals circadian time in a blood sample

A researcher at Vanderbilt has identified a set of 15 genes that together exhibit a 24-hour gene expression pattern in human blood, constituting a circadian clock biomarker.

Researchers chart new informatics path in tracking disease risk

In a study in Circulation: Cardiovascular Genetics, Vanderbilt University’s Jonathan Mosley, M.D., Ph.D., and colleagues use genetic correlation to hitch together two unrelated sets of data, one from a longstanding epidemiological cohort and the other from electronic health records.

Bioinformatics expert Omenn to speak Feb. 25

Gilbert Omenn, M.D., Ph.D., director of the University of Michigan Center for Computational Medicine and Bioinformatics, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 25.