blood vessel

close up of blood vessels
October 25, 2022

Vascular dysfunction during sepsis

Regulation of the enzyme Sirtuin 1 in blood vessel endothelial cells may drive altered metabolism and vascular dysfunction during sepsis, Vanderbilt researchers have discovered.

By Leigh MacMillan
March 29, 2022

There’s no slowing arterial stiffening

Over 10 years, multiple healthy behaviors did not slow the progression of arterial stiffness, a risk factor for coronary artery disease, hypertension, stroke, atrial fibrillation and heart failure.

By Paul Govern
May 4, 2021

New strategy to treat brain bleeding

Vasorelaxing peptides could offer a promising therapeutic strategy for reducing the neurological deficits caused by subarachnoid hemorrhage-induced cerebral blood vessel constriction.

By Leigh MacMillan
close up of blood vessels
October 15, 2020

Brain blood vessel response to hypoxia

The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered.

By Leigh MacMillan
August 20, 2020

A “torque” for tumor blood vessels

Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.

By Bill Snyder
October 12, 2016

Imaging probe for retinal disease

An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness.

By Leigh MacMillan
September 4, 2015

Vitamin C protects blood vessel lining

Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.
By Leigh MacMillan
September 3, 2014

Aggressive bone cancers build more blood vessels

A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.
By Katherine Venmar
February 7, 2014

New direction for treating lung cancer

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.
By Leigh MacMillan
December 18, 2013

Targeting tumor “supply lines”

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies.
By Leigh MacMillan
August 26, 2013

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.
By Leigh MacMillan
April 15, 2013

A role for blood vessels in delirium?

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.
By Leigh MacMillan
February 4, 2013

Brain tumor TIP reveals new target

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.
By Leigh MacMillan