bone fracture

Research by Christopher Peek, PhD, left, Jim Cassat, MD, PhD, and their colleagues reveals how gut inflammation leads to bone loss.
August 25, 2022

Vanderbilt researchers discover how gut inflammation leads to bone loss

Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.

By Leigh MacMillan
January 10, 2020

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.

By Leigh MacMillan
June 15, 2017

Unal receives Orthopedic Research Society award

Mustafa Unal, Ph.D., a postdoctoral research fellow at Vanderbilt University School of Medicine, has been selected by the Orthopedic Research Society to receive its 2017 Alice L. Jee Young Investigator Award for work that potentially will improve the clinical assessment of bone strength and quality.

By Bill Snyder
August 13, 2015

VUMC study shifts thinking on how bone fractures heal

New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal.

By Leigh MacMillan
May 6, 2015

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

By Leigh MacMillan
September 11, 2014

Bone healing therapy for NF1 fractures

A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.

By VUMC News and Communications
June 16, 2014

Factor impacts bone toughness

The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets.
By Leigh MacMillan