bone fracture

Research by Christopher Peek, PhD, left, Jim Cassat, MD, PhD, and their colleagues reveals how gut inflammation leads to bone loss.

Vanderbilt researchers discover how gut inflammation leads to bone loss

Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.

Unal receives Orthopedic Research Society award

Mustafa Unal, Ph.D., a postdoctoral research fellow at Vanderbilt University School of Medicine, has been selected by the Orthopedic Research Society to receive its 2017 Alice L. Jee Young Investigator Award for work that potentially will improve the clinical assessment of bone strength and quality.

VUMC study shifts thinking on how bone fractures heal

New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal.

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

Bone healing therapy for NF1 fractures

A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.