bone

September 14, 2023

Bone metabolism changes with aging

Vanderbilt researchers have detailed how aging alters the metabolism of bone-forming cells, which could contribute to age-related osteoporosis.

By Leigh MacMillan
September 27, 2022

Diagnostic biomarker for bone disorder

A urine chemical performs better as a diagnostic biomarker for the soft bone disease hypophosphatasia than other laboratory measures, Vanderbilt researchers have demonstrated.

By Leigh MacMillan
January 10, 2020

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.

By Leigh MacMillan
April 11, 2019

Keeping bone in its place

Jonathan Schoenecker and colleagues have discovered a new mechanism for the formation of bone in soft tissues — a complication of severe injuries that causes pain and limits mobility.

By Anivarya Kumar
August 9, 2017

Stress may switch on bone “mets”

New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes.

By Bill Snyder
June 15, 2017

Unal receives Orthopedic Research Society award

Mustafa Unal, Ph.D., a postdoctoral research fellow at Vanderbilt University School of Medicine, has been selected by the Orthopedic Research Society to receive its 2017 Alice L. Jee Young Investigator Award for work that potentially will improve the clinical assessment of bone strength and quality.

By Bill Snyder
December 8, 2016

Plasmin prevents muscle ‘hardening’ after injury: study

Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.
By Leigh MacMillan
May 6, 2015

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.
By Leigh MacMillan
January 14, 2015

Inner ear keeps bones strong

Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel.
By Matthew Correia
August 7, 2014

Novel treatment strengthens bones in genetic disease

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.
By Leigh MacMillan
June 16, 2014

Factor impacts bone toughness

The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets.
By Leigh MacMillan
November 7, 2013

Neurotransmitter’s role in bone balance

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.
By Leigh MacMillan
July 31, 2013

Factor’s role in long bone development

Insight into how the protein neurofibromin participates in the signaling pathway that produces the body’s long bones has implications for fracture healing in some patients.
By Leigh MacMillan
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