breast cancer

Ann Richmond, MD, Chi Yan, PhD, Jinming Yang, PhD, and colleagues are studying ways to boost antitumor immunity and reduce tumor growth in breast cancer and melanoma.
December 17, 2020

Study reveals new strategy for reducing tumor growth, metastasis

A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.

By Leigh MacMillan
November 12, 2020

Breast cancer treatment in older women

A new study from Vanderbilt epidemiologists suggests that it’s time to reconsider clinical practice guidelines for the treatment of early-stage breast cancer in older women.

By Leigh MacMillan
November 5, 2020

Screening younger women for hereditary cancers may be cost effective

Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open.

By Tom Wilemon
August 6, 2020

The importance of estrogen cycles

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

By Sarah E. Glass
March 12, 2020

Triple-negative breast cancer drug therapy shows promise

Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation.

By Tom Wilemon
February 27, 2020

Breast cancer study may help predict treatment response

Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat.

By Bill Snyder
February 10, 2020

Imaging breast cancer cell size

A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.
By Leigh MacMillan
January 23, 2020

HDL-cholesterol and breast cancer risk

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.
By Leigh MacMillan
January 16, 2020

ACMG issues statement on breast cancer genetic testing

According to a statement on behalf of the American College of Medical Genetics and Genomics, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.
By Tom Wilemon
December 13, 2019

The American College of Medical Genetics and Genomics advises evaluating all breast cancer patients to determine the need for genetic testing

According to a statement on behalf of the American College of Medical Genetics and Genomics, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.
By Tom Wilemon
November 20, 2019

Study finds breast cancer recurrence score has different implications for men

A study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence. However, a new study finds this conclusion may not directly apply to male patients with the same type of breast cancer
By Tom Wilemon
October 24, 2019

Breast cancer research pioneer Page remembered

David Page, MD, former professor of Pathology and Preventive Medicine at Vanderbilt University School of Medicine, whose work revolutionized the assessment of breast cancer risk, died in Nashville on Thursday, Oct. 17. He was 78.
By Bill Snyder
October 24, 2019

Pietenpol, Wilson land Komen cancer research support

Two Vanderbilt-Ingram Cancer Center investigators have received financial support from Susan G. Komen for breast cancer research.
By Tom Wilemon
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