cardiovascular disease

May 24, 2022

Diabetes, cardiovascular drug targets

Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Leigh MacMillan
April 11, 2022

Peptides promote AFib arrhythmia

Peptide oligomers have detrimental metabolic effects and cause pro-arrhythmic electrophysiological changes in heart atria, suggesting they may contribute to atrial fibrillation.

By Leigh MacMillan
March 7, 2022

Study finds World Trade Center responders at higher risk for blood cancer-associated mutations

A study by Vanderbilt and New York City researchers found that 9/11 first responders to the World Trade Center have increased levels of mutations that escalate their risk for blood cancers or cardiovascular disease

By Tom Wilemon
PHOTO: Members of the supermere discovery team include (front row from left) Qi Liu, PhD, Robert Coffey, MD, Qin Zhang, PhD, and (back row from left) James Higginbotham, PhD; Dennis Jeppesen, PhD; and Jeffrey Franklin, PhD. (hoto by Erin O. Smith)
December 10, 2021

“Supermeres” may carry clues to cancer, Alzheimer’s disease and COVID-19

Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19.

By Bill Snyder
Officials cut the ribbon at last week’s dedication of VUMC’s new hybrid operating rooms.
November 2, 2021

VUMC debuts two new state-of-the-art hybrid operating rooms

Vanderbilt is opening two of the newest generation of hybrid operating rooms, which each combine a traditional operating room with the latest advanced imaging equipment.

By Matt Batcheldor
August 19, 2021

Potential protection from atherosclerosis

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.

By Bill Snyder
August 12, 2021

Study reveals missing link between high-fat diet, microbiota and heart disease

A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.
By Leigh MacMillan
August 12, 2021

Wanjalla honored by Doris Duke Foundation

Celestine Wanjalla, MD, PhD, assistant professor of Medicine in the Division of Infectious Diseases, is among 17 recipients of the Doris Duke Charitable Foundation 2021 Clinical Scientist Development Award.
By Paul Govern
August 10, 2021

Vitamin D impact on disease biomarkers

In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.
By Leigh MacMillan
July 12, 2021

Probing statin-associated diseases with genetics

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.
By Leigh MacMillan
May 20, 2021

VUMC is pacesetter for national aspirin study

According to an innovative large-scale clinical trial reported last week in the New England Journal of Medicine, a single daily baby aspirin (81 mg) or a single daily adult aspirin (325 mg) are equally safe and effective for prevention of adverse cardiovascular events for patients with established atherosclerotic cardiovascular disease.
By Paul Govern
August 20, 2020

Salt, immune cells and hypertension

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption.
By Leigh MacMillan
July 27, 2020

Soy food, metabolism and the microbiome

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered.
By Sarah E. Glass
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