chemistry

Insights for neuroscience drug discovery

When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.

Neurons with serotonin transporters labeled with quantum dots. (Jerry Chang / Vanderbilt)

Probing the roots of depression by tracking serotonin regulation at a new level

An interdisciplinary team of scientists have successfully tagged a protein that regulates the neurotransmitter serotonin with tiny fluorescent beads, allowing them to track the movements of individual molecules for the first time. This capability makes it possible to study the manner in which serotonin regulates mood, appetite and sleep at a new level of detail.

DNA: From modification to mutation

Understanding how an environmental hazard damages DNA may shed light on processes of tumor formation.

Neuronal clues to cholesterol-defect disorder

Antioxidants may be a beneficial treatment for an inherited genetic disorder.

moldy bread

Fungus toxin gets in the way in DNA

Structural studies are providing insight to how aflatoxin – a toxin produced by fungi – contributes to cancer development.

Kudos

Read about Vanderbilt faculty, staff, student and alumni’s latest awards, appointments and achievements

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