Children's Tumor Foundation

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

Novel treatment strengthens bones in genetic disease

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

Skeletal defects in genetic disorder

A new mouse model provides a tool for testing novel therapeutic approaches for neurofibromatosis.