Children's Tumor Foundation Archive — Page 1 of 1

Three anatomical views of a human skeleton on a white background: front, side, and back.
May 6, 2015

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

By Leigh MacMillan
Microscopic bone tissue showing black calcified bone beside a broad pink region of non-calcified osteoid, with orange-brown bone-forming cells lining the osteoid.
August 7, 2014

Novel treatment strengthens bones in genetic disease

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

By Leigh MacMillan
Three anatomical views of a human skeleton on a white background: front, side, and back.
November 18, 2011

Skeletal defects in genetic disorder

A new mouse model provides a tool for testing novel therapeutic approaches for neurofibromatosis.

By Leigh MacMillan