David Jacobson

First Islet Workshop draws international audience

More than 200 investigators from across the globe who specialize in islet biology, the study of hormone-producing cell clusters in the pancreas known as islets, recently gathered in Nashville to share knowledge and present the challenges and successes of their work during the first Islet Biology Workshop at Vanderbilt.

Cellular calcium handling in diabetes

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

Insulin in vials

CaMKII enhances insulin secretion

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.