Department of Cell and Developmental Biology

The extracellular RNA in colorectal cancer team includes, from left, Jeffrey Franklin, PhD, Yu Shyr, PhD, Qi Liu, PhD, Alissa Weaver, MD, PhD, James Higginbotham, PhD, and James Patton, PhD. Not pictured: Robert Coffey, MD, Kasey Vickers, PhD, and John Karijolich, PhD. (photo taken before social distancing)
April 9, 2020

Research team awarded $9 million to study extracellular RNA in colorectal cancer

The NCI program project grant is supporting multiple projects that aim to define fundamental biological principles about extracellular RNA signaling and the development and aggressiveness of colorectal cancer, the second leading cause of cancer death in the United States.

By Leigh MacMillan
March 5, 2020

Clues to lung injury in preterm babies

Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth.

By Leigh MacMillan
January 29, 2020

Protein research seeks to induce tumor regression

Understanding how MYC interacts with WDR5 and other cofactors could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks.

By Bill Snyder
January 23, 2020

Insights on diabetic retinopathy

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

By Leigh MacMillan
x-ray of stomach
January 16, 2020

VUMC study sheds light on gastric cancer development

VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.

By Bill Snyder
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

By Leigh MacMillan
December 4, 2019

Genetic screen in worms reveals critical step in insulin synthesis

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.
By Leigh MacMillan
November 18, 2019

Understanding cell division

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.
By Cayetana Arnaiz Yépez
November 14, 2019

VUMC researchers set for Cutting-Edge Discovery Lecture

Antiviral immunity, obesity and pulmonary fibrosis will be discussed by three Vanderbilt University researchers during a Cutting-Edge Discovery Lecture on Nov. 21. The lecture will begin at 4 p.m. in 208 Light Hall.
By Leigh MacMillan
October 17, 2019

Microscopic spines connect worm neurons

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology.
By Leigh MacMillan
September 19, 2019

Microvilli in motion

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.
By Anivarya Kumar
September 5, 2019

The plus and minus of microtubules

Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.
By Bill Snyder
August 27, 2019

A “rheostat” for cancer signals

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.
By Sanjay Mishra
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